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. 2021 Sep 30;26(6):e12894. doi: 10.1111/anec.12894

TABLE 2.

Contemporary analytical approaches to sudden cardiac death risk stratification in Health Survey 2000

Electrocardiographic marker Multivariable adjusted odds ratio for sudden cardiac death (95% CI) Significance (p values)
Interval markers in single leads
QTNC 1.2 (1.01–1.5) .044
QTF 1.2 (0.996–1.5) .054
Tpeak–Tend in lead V5 0.9 (0.8–1.2) .620
Vectorcardiographic markers
Principal component analysis ratio 1.1 (0.9–1.4) .367
T‐wave morphology dispersion 1.4 (1.1–1.7) .001
Total cosine R‐to‐T 1.3 (1.1–1.6) .013
T‐wave residuum 1.2 (1.0–1.5) .050
Second central moment in multiple leads
RWH (≥470 mV) 1.2 (0.8–2.0) <.05
JWH (≥123 mV) 2.0 (1.2–3.3) <.01
TWH (≥102 mV) 1.7 (1.0–2.9) <.05
JWH + TWH 2.9 (1.5–5.7) <.01
RWH + JWH + TWH 3.2 (1.4–7.1) <.01

Abbreviations: CI, confidence interval; JWH, J‐wave heterogeneity; QTF, QT interval with the Frederica formula for adjustment of heart rate; QTNC, QT interval with the nomogram method for adjustment of heart rate; RWH, R‐wave heterogeneity; TWH, T‐wave heterogeneity.

Data are from Kenttä et al. (2016) and Porthan et al. (2013). Table is reprinted with permission from Verrier and Huikuri (2017)