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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: J Acquir Immune Defic Syndr. 2021 Aug 1;87(Suppl 1):S43–S51. doi: 10.1097/QAI.0000000000002704

Table 3:

Expected sample size and precision under targeted child sample designs, by country: Population-based HIV Impact Assessment, 2015 -- 2017


Country
Lesotho Malawi Namibia Eswatini Tanzania Uganda Zambia Zimbabwe

Overall HIV prevalence for children age 0–14 (%) 2.1% 1.5% 1.0% 2.8% 0.4% 0.5% 1.1% 1.6%
Prevalence for children with HIV positive or deceased mothers (%) 5.3% 8.5% 5.2% 7.6% 6.3% 4.6% 6.9% 7.2%
Prevalence for children with unknown HIV status mothers (%) 1.7% 2.0% 0.8% 2.1% 0.2% 0.7% 1.0% 1.7%
Prevalence for children with HIV negative mothers (%) 0.05% 0.11% 0.06% 0.08% 0.01% 0.07% 0.05% 0.05%
Proportion of all rostered children with positive or deceased mothers 26% 12% 13% 27% 7% 7% 12% 15%
Proportion of all rostered children with unknown status mothers 39% 29% 46% 37% 25% 24% 29% 34%
Proportion of all rostered children with negative mothers 35% 59% 41% 36% 69% 69% 60% 50%
Neyman allocation sampling fractions (after accounting for non-response)
 Children with positive or deceased mothers 90% 78% 95% 92% 97% 95% 85% 88%
 Children with unknown status mothers 52% 39% 37% 50% 16% 38% 34% 44%
 Children with negative mothers 9% 9% 10% 10% 4% 12% 7% 7%
Expected number of children tested 4,606 5,260 5,101 3,607 4,253 7,305 5,618 6,196
Scenario 1: Neyman allocation design
 Expected design effect under optimal allocation 0.69 0.64 0.63 0.71 0.35 0.54 0.50 0.61
 Expected RSE 8% 9% 11% 8% 14% 12% 9% 8%
Scenario 2: Modified Neyman allocation with sample reallocated from children with negative mothers
 Expected design effect 0.60 0.57 0.52 0.62 0.25 0.58 0.40 0.51
 Expected bias in estimated prevalence −0.02% −0.06% −0.02% −0.03% −0.01% −0.05% −0.03% −0.02%
 Expected RRMSE 8% 8% 10% 8% 12% 12% 8% 7%
 Proportional reduction in MSE, compared to PHIA subsample design with equal sample size (Scenario 3) 33% 43% 33% 27% 61% 50% 43% 46%
Scenario 3: PHIA sub-sample design pro-rated to optimal allocation sample size
 Expected RSE 12% 14% 15% 11% 31% 24% 14% 13%
Actual PHIA results using the 50% household subsample design
 Number of children tested 3,966 6,166 6,761 3,372 9,616 10,345 8,015 7,032
 RSE 13% 13% 13% 11% 21% 20% 11% 12%