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. 2021 Oct 31;26(21):6606. doi: 10.3390/molecules26216606

Table 3.

Various analytical devices for determining adulterated drugs in herbal medicine.

Analyte Matrix Method Media LOD/LOQ %RSD/
Recovery
Reference
Paracetamol Herbal medicine powder Optical sensor membrane Polymer poly(methyl methacrylate) (PMMA) Lowest measurable: 2.55–4.01 mg/mL - [22]
Allopurinol Herbal medicine powder A paper-based analytical device using colorimetry Whatman filter paper No. 1, 4, 6 and
Whatman 1 chromatography
Lowest measurable: 75 mg/mL - [13]
Dexamethasone and
Prednisolone
Herbal medicine pellets Electrochemical paper-based analytical device Whatman SG81 paper LOD
dexamethasone: 3.59 µg/mL
prednisolone: 11.988 µg/mL
LOQ
Dexamethasone: 6.00 µg/mL
prednisolone: 20.02 µg/mL
Dexamethasone: 83 to 108% (recovery) and 5.6 to 10.1% (Coefficient of variation)
prednisolone: 88 to 134% (recovery) and 4.4 to 13.8% (coefficient of variation)
[6]
Sibutramine Powder (weight loss product) A distance-based paper device with colorimetry Filter paper LOQ
0.22 mmol/L
Less than 4.4%RSD [58]
Dexamethasone Powder (joint-paint killer product) Dipstick test using sensing film Cellulose acetate film LOD: 0.422 μg/mL
LOQ: 1.406 μg/mL
Recovery: 99.978–101.144%
RSD: <0.196%
[59]