TABLE 4.
Characteristics of the patients alive or deceased in the coronavirus disease 2019 (COVID-19) cohort and stratification by geographical origin
| Vital status | Geographical location | |||||
| Alive # | Deceased ¶ | p-value | Europe | Not Europe | p-value | |
| Patients | 682 | 85 | 289 | 478 | ||
| Age, years | 41 (30–55) | 65 (48–77) | <0.0001 | 49 (36–63) | 39 (29–54) | <0.0001 |
| Age ≥65 years | 83 (12.2) | 44 (51.8) | <0.0001 | 68 (23.5) | 59 (12.3) | <0.0001 |
| Males | 470 (68.9) | 70 (82.4) | 0.01 | 209 (72.3) | 331 (69.3) | 0.37 |
| Non-European | 434 (63.6) | 44 (51.8) | 0.03 | |||
| ≥1 comorbidity | 343 (50.3) | 73 (85.9) | <0.0001 | 183 (63.3) | 233 (48.7) | <0.0001 |
| ≥2 comorbidities | 147 (21.6) | 49 (57.7) | <0.0001 | |||
| Number of comorbidities | 1 (0–1) | 2 (1–4) | <0.0001 | |||
| Diabetes mellitus | 125 (18.3) | 32 (37.7) | <0.0001 | 63 (21.8) | 94 (19.7) | 0.48 |
| Cardiovascular disease | 105 (15.4) | 41 (48.2) | <0.0001 | 79 (27.3) | 67 (14.0) | <0.0001 |
| Chronic respiratory disease | 71 (10.4) | 22 (25.9) | <0.0001 | 46 (15.9) | 47 (9.8) | 0.01 |
| HIV | 68 (10.0) | 12 (14.1) | 0.14 | 25 (8.7) | 55 (11.5) | 0.21 |
| Chronic liver disease | 50 (7.3) | 10 (11.8) | 0.15 | 47 (16.3) | 13 (2.7) | <0.0001 |
| Chronic renal disease | 38 (5.6) | 15 (17.7) | <0.0001 | 33 (11.4) | 20 (4.2) | <0.0001 |
| Invasive ventilation | 15 (2.7) | 31 (41.3) | <0.0001 | 14 (5.0) | 32 (9.3) | 0.04 |
| Previous TB | 200 (30.2) | 34 (40.0) | 0.07 | 79 (27.7) | 155 (33.6) | 0.09 |
| Hospitalisation due to COVID-19 | 381 (59.0) | 71 (83.5) | <0.0001 | 220 (76.4) | 232 (52.3) | <0.0001 |
| Duration of hospitalisation, days | 14 (8–22) | 10 (4–24) | 0.007 | 14 (9–22) | 13 (6–24) | 0.11 |
| Concomitant hospitalisation due to TB/COVID-19 co-infection | 216 (31.7) | 34 (40.0) | 0.19 | 136 (31.7) | 114(40.0) | 0.005 |
| Duration of concomitant hospitalisation | 16 (10–24) | 8 (4–20) | 0.11 | 16 (11–22) | 14 (6–26) | 0.36 |
| Death | 41 (14.2) | 44 (9.2) | 0.03 | |||
| Death at age ≥65 years | 26/41 (63.4) | 18/44 (40.9) | 0.04 | |||
| Age of patients who died, years | 70 (59–80.5) | 57.5 (44.3–71.8) | 0.004 | |||
| Dead with ≥1 comorbidity | 38/183 (20.8) | 35/233 (15.0) | 0.13 | |||
| Dead with diabetes mellitus | 19/63 (30.2) | 13/94 (13.8) | 0.01 | |||
| Dead with cardiovascular disease | 26/79 (32.9) | 15/67 (22.4) | 0.16 | |||
| Dead with chronic respiratory disease | 13/46 (28.3) | 9/47 (19.2) | 0.30 | |||
| Dead with HIV | 3 (12.0) | 9 (16.4) | 0.61 | |||
| Dead with chronic liver disease | 7/47 (14.9) | 3/13 (23.1) | 0.68 | |||
| Dead with chronic renal disease | 11/33 (33.3) | 4/20 (20.0) | 0.30 | |||
| Dead with active TB | 20/206 (9.7) | 31/307 (10.1) | 0.89 | |||
Data are presented as n, median (interquartile range) or n/N (%), unless otherwise stated. TB: tuberculosis. #: all patients in the cohort based on the latest information available (see text and figure 3 for details); ¶: all patients who died based on the latest information available. The detailed causes of death are reported in the text and in figure 3.