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. 2021 Nov 12;434(2):167357. doi: 10.1016/j.jmb.2021.167357

Table 2.

The affinity of the RBD – ACE2 interaction in the presence of disulfide-reducing agents at 37 °C determined from microscale thermophoresis (MST).

Affinity (µM)
No compound 0.12 ± 0.05
2.5 mM TCEP 13.3 ± 4.0*
2.5 mM DTT 21.9 ± 13.6*
2.5 mM DTT oxidized 0.17 ± 0.08
10 mM NAC 0.57 ± 0.40
10 mM GSH 0.60 ± 0.38
*

Significant at p < 0.05.