Table 2.
Univariate and multivariate survival analyses (proportional hazards method) for patients with primary HNSCC
| Parameters | Univariate survival analysis | Multivariate survival analysis | ||||
|---|---|---|---|---|---|---|
| Hazard ratio | 95% CI | P values | Hazard ratio | 95% CI | P values | |
| Gender(male, female) | 1.527 | 0.691–3.374 | 0.296 | 1.969 | 0.665–5.830 | 0.221 |
| Smoking(Yes, No) | 1.484 | 0.591–3.727 | 0.401 | 1.473 | 0.308–7.049 | 0.628 |
| Alcohol use (Yes, No) | 0.681 | 0.282–1.643 | 0.392 | 0.428 | 0.118–1.551 | 0.196 |
| Age (> 60, ≤60) | 0.682 | 0.311–1.496 | 0.340 | 0.529 | 0.224–1.246 | 0.145 |
| Tumor size (T3-T4, T1-T2) | 0.747 | 0.312–1.792 | 0.514 | 0.842 | 0.329–2.158 | 0.720 |
| Pathological grade (II-III, I) | 0.622 | 0.213–1.813 | 0.384 | 0.645 | 0.188–2.221 | 0.487 |
| Cervical nodal metastasis (N+, N0) | 1.175 | 0.536–2.578 | 0.687 | 0.881 | 0.359–2.157 | 0.781 |
| Clinical stage (III-IV, I-II) | 1.558 | 0.685–3.545 | 0.290 | 1.272 | 0.517–3.13 | 0.600 |
| FOXD1 expression (high, low) | 4.159 | 1.626–10.641 | 0.003 | 4.926 | 1.728–14.045 | 0.003 |
Bold indicates statistical significance, with P values less than 0.05