Fig. 1.
Illustration of phase gated PET and the proposed method. The Anzai signal (red curve) can guide the assignment of the detected events to different respiratory phases and generate 6 gated images. End-expiration gate with the least intra-gate motion (G4) is used as our reference gate. Our goal is to register all the low-dose gated images to the reference gate, averaging them, and denoise the averaged image to generate a high-dose gated image at the reference gate with the least intra-gate motion.