Table 1.
Parameters analysed in ten patients at baseline and after 1-month treatment
| Patients characteristics | Baseline values | T1 values | p-values | Holm-Bonferroni method | |
|---|---|---|---|---|---|
| Age (years) | 69.30 ± 3.62 | ||||
| Height (cm) | 175.80 ± 5.51 | ||||
| Weight (Kg) | 86.04 ± 6.91 | 84.69 ± 6.56 | 0.002 | 0.004 | |
| BMI (kg/m2) | 27.81 ± 1.32 | 27.38 ± 1.33 | 0.001 | 0.003 | |
| Waist Circumference (cm) | 115.80 ± 4.64 | 110.80 ± 4.85 | 0.003 | 0.004 | |
| HOMA-IR Index | 5.41 ± 1.71 | 3.52 ± 1.02 | 0.001 | 0.003 | |
| Glycaemia (mg/dL) | 103.10 ± 11.14 | 91.10 ± 6.89 | 0.001 | 0.004 | |
| Insulin (µIU/L) | 21.34 ± 6.27 | 15.64 ± 4.29 | 0.004 | 0.006 | |
| Testosterone (ng/dL) | 222.80 ± 5.59 | 262.80 ± 32.11 | 0.009 | 0.007 | |
| Androstenedione (ng/mL) | 0.43 ± 0.12 | 0.88 ± 0.23 | 0.002 | 0.004 | |
| Oestradiol (pg/mL) | 42.24 ± 4.32 | 34.15 ± 5.36 | 0.018 | 0.007 | |
| Oestrone (pg/mL) | 128.59 ± 5.60 | 93.59 ± 13.67 | 0.001 | 0.003 | |
| T/E2 Ratio | 5.31 ± 1.11 | 7.83 ± 2.04 | 0.019 | 0.031 | |
| LH (mIU/mL) | 12.61 ± 2.67 | 9.76 ± 1.64 | 0.005 | 0.007 | |
| Strength Test (Kg) | 24.98 ± 1.74 | 27.10 ± 2.07 | 0.004 | 0.005 | |
| IIEF Questionnaire | 11.50 ± 1.96 | 13.60 ± 1.96 | 0.001 | 0.003 | |
Characteristics of patients involved in the study at baseline and after one-month treatment. Data are shown as mean ± SD. The statistical analysis are performed via Student’s paired T-Test and fixed via Holm-Bonferroni method
T1 after 30 days of treatment; BMI Body-mass Index, HOMA-IR Homeostatic Model Assessment for Insulin Resistance, T/E2 Testosterone/Oestradiol ratio, LH Luteinizing Hormone, IIEF International Index of Erectile Function