Skip to main content
. 2021 Oct 29;12:746647. doi: 10.3389/fimmu.2021.746647

Figure 5.

Figure 5

Construction of m1A signatures. (A) Alluvial diagram showing the changes of m1Aclusters, gene cluster, m1Ascore and patient survival status. (B) Correlations between m1Ascore and the known gene signatures using Spearman analysis. Negative correlation was marked with blue and positive correlation with red. (C) Differences in m1Ascore among three gene clusters. (D) Differences in m1Ascore among three m1A modification patterns. (E) The correlation between m1Ascore and several immune cell, including resting dendritic cells, macrophages M1, resting memory CD4+ T cells, CD8+ T cells, follicular helper T cells and gamma delta T cells. (F) The abundance of each TME infiltrating cell in low- and high-m1Ascore group. (G) Enrichment plots showing cell cycle, citrate cycle TCA cycle, DNA replication, mismatch repair, and oxidative phosphorylation pathways were enriched in the low m1Ascore subgroup. *P < 0.05; **P < 0.01; ***P < 0.001. ns, not significant.