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. 1999 Dec;37(12):4099–4106. doi: 10.1128/jcm.37.12.4099-4106.1999

TABLE 2.

Nature and frequency of amino acid substitutions at resistance-associated codons in the protease gene: cross-sectional analysis of 285 sequences

Mutation at the following codona:
10 (L) 20 (K) 24 (L) 30 (D) 32 (V) 33 (L) 36 (M) 46 (M) 48 (G) 54 (I) 63 (L) 71 (A) 77 (V) 82 (V) 84 (I) 88 (N) 90 (L) 93 (I)
I (44) R (11) I (3) N (3) I (3) V (9) I (48) I (12) V (9) V (18) P (203) V (36) I (58) A (30) V (8) S (2) M (21) L (54)
V (10) I (6) I (2) L (4) L (11) Q (1) I (9) S (19) T (21) A (1) I (5) L (2) D (1) F (1)
F (3) M (6) R (1) R (1) T (2) A (17) I (2) L (1) F (3) G (1) N (1)
L (1) V (1) A (1) H (10) P (1) T (1) T (2)
Q (1) S (1) V (5) M (1) C (1)
T (1) F (2) D (1)
C (1) G (1)
D (1)
I (1)
N (1)
Q (1)
a

See footnote a of Table 1