Table 2.

The effects of acetaminophen and saffron extract treatment on serum concentration of aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH) and alkaline phosphatase (ALP)

	AST	ALT	LDH	ALP
Control	106.21±2.49	72.00±2.42	702.66±72.61	822.24±46.87
Vehicle	105.83±5.26	70.21±3.27	721.66±31.97	783.24±40.00
Acetaminophen	161.20±14.80**	135.65±24.7*	1327.41±158.10**	817.56±56.60
Saffron-150	102.40±3.06†††	74.71±4.69††	874.32±61.50††	767.64±47.12
Saffron-300	102.74±5.22†††	64.54±4.00†††	693.80±46.32†††●	739.01±29.50

*Significant differences from the control group (*p≤0.05 and **p≤0.01); †significant differences from the acetaminophen-treated group (††p≤0.01 and †††p≤0.001); ●significant differences from the saffron-treated 150 mg/kg/day (●p≤0.05)