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. 2021 Nov 9;135(21):2521–2540. doi: 10.1042/CS20210370

Figure 1. Schematic representation of renal cysts morphology in ADPKD and ARPKD.

Figure 1

A healthy nephron with major segments is shown on the left. In ADPKD (middle image), cysts can form in any nephron segments (including glomeruli); however, they are primarily located in distal regions and the CD. The cysts grow and eventually detach from the rest of the tubule but continue to accumulate fluid. In ARPKD (right image), cysts are formed in the distal nephron, mainly the CDs, and are presented by dilated tubules, which remain connected with the rest of the nephron. Abbreviation: G, glomerulus; CD, collecting duct.