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. 2021 Oct 29;12:757088. doi: 10.3389/fendo.2021.757088

Table 2.

Differential metabolites identified from metabolomics profiling.

Metabolite name Mode VIP FC P Value Subclass
Pantothenic acid POS 1.53 1.553 0.0057 vitamin
(–)-Riboflavin POS 2.05 2.819 0.0076 vitamin
D-(+)-Pantothenic acid NEG 1.16 1.357 0.0310 vitamin
Pseudouridine NEG 1.63 1.720 0.0047 uridine
D-GLUCURONIC ACID NEG 1.30 1.316 0.0455 sugars
Dehydroisoandrosterone sulfate NEG 1.19 0.598 0.0456 steroids
Hypoxanthine NEG/POS 2.60 0.360 0.0079 purine derivatives
N2,N2-Dimethylguanosine POS 1.11 1.439 0.0331 nucleoside
sn-Glycero-3-phosphocholine POS 1.01 0.705 0.0301 lipid
Propionylcarnitine POS 1.05 1.276 0.0267 lipid
Acetylcarnitine POS 1.38 1.584 0.0088 enzyme
Inosine NEG/POS 2.18 0.315 0.0363 creatinine
Cholic acid NEG/POS 2.53 0.244 0.0172 cholic acid
Butyryl carnitine POS 1.48 1.561 0.0024 carnitine
UROCANIC ACID POS 1.33 1.373 0.0002 azole
N-Fructosyl isoleucine POS 1.09 1.496 0.0474 amino acid
N-acetyltryptophan POS 1.95 3.762 0.0341 amino acid
Leucylleucine POS 3.24 0.329 0.0002 amino acid
Kynurenic acid POS 1.90 0.541 0.0000 amino acid
3-Methylhistidine POS 1.86 2.264 0.0010 amino acid
Phenylacetylglutamine NEG/POS 2.10 3.262 0.0188 amino acid
Glutamine NEG 1.98 2.560 0.0196 amino acid

POS, Positive; NEG, Negative; FC, Fold change; VIP, Variable important in projection.