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. 2021 Oct 29;8:750047. doi: 10.3389/fsurg.2021.750047

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Copyright © 2021 Xin, Tan, Li, Chen, Zhang, Li, Yang, Xing, Zhou, Tian, Lv and Zhu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of factors relating serum MMP-13 with osteoarthritic symptoms and radiographic severity. Correlations between plasma MMP-13 levels and (A) pain scores, (B) stiffness scores, (C) function scores, (D) total Western Ontario and McMaster Universities Osteoarthritis Index scores, (E) Kellgren–Lawrence grading in all patients, (F) serum MMP-13 levels in patients with and without OA. Value = mean ± standard error of the mean. OA, osteoarthritis. *p < 0.05; ^#indicates the difference was statistically significant (p < 0.05).