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. 2021 Oct 29;8:750047. doi: 10.3389/fsurg.2021.750047

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Copyright © 2021 Xin, Tan, Li, Chen, Zhang, Li, Yang, Xing, Zhou, Tian, Lv and Zhu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Relative variable importance of each predictor in the full model of OA grouped by risk factors related to laboratory and patient. The factors for knee OA were involved in the full model. Patient age was the major risk factor for knee OA in the full model. Despite the AIC value of <2, MMP-13 was also a major risk factor for knee OA compared with other laboratory-related factors. ESR, erythrocyte sedimentation rate; PT-A, plasma thromboplastin antecedent; PT, prothrombin time; CRP, C-reactive protein; Neu%, neutrophil ratio; Hb, hemoglobin; Cr, creatinine; ESR, erythrocyte sedimentation rate; FIB, fibrinogen; WBC, white blood cell count; AST, aspartate aminotransferase; APTT, activated partial thromboplastin time; FDP, fibrin degradation product; PLT, platelet count; ALT, alanine aminotransferase; ALB, albumin level; INR, international normalized ratios; BMI, body mass index.