Table 2.

Predictive factors of knee osteoarthritis for model 1 (patient-and laboratory-related factors) and model 2 (laboratory-related factors).

Variable	Model 1		Model 2
	OR (95% CI)	P-value	OR (95%CI)	P-value
Patient-related risk factors
Age	1.02 (1.01–1.03)	<0.001**
Sex
Female	1.06 (0.73–1.56)	0.755
Male	—	—
BMI	1.00 (0.98–1.02)	0.950
Laboratory-related risk actors
MMP-13	1.03 (0.99–1.08)	0.166	1.07 (1.01–1.13)	0.037*
CRP (mg/L)	1.02 (0.99–1.05)	0.214	1.03 (0.99–1.07)	0.207
ESR (mm/H)	0.99 (0.98–1.01)	0.518	0.99 (0.97–1.01)	0.347
WBC	1.02 (0.94–1.11)	0.672	1.01 (0.90–1.13)	0.884
Neu (%)	0.99 (0.98–1.00)	0.132	0.98 (0.97–1.00)	0.061
Hb	0.99 (0.98–1.01)	0.271	1.00 (0.98–1.01)	0.572
PLT	1.00 (0.99–1.00)	0.789	1.00 (0.99–1.00)	0.041*
Alb (g/L)	1.00 (0.98–1.02)	0.925	1.00 (0.97–1.03)	0.895
ALT (U/L)	1.00 (0.98–1.02)	0.840	0.99 (0.96–1.01)	0.308
AST (U/L)	1.01 (0.97–1.04)	0.743	1.03 (0.98–1.08)	0.252
Cr (mmol/L)	1.00 (1.00–1.00)	0.515	1.00 (1.00–1.00)	0.463
PT(S)	0.35 (0.08–1.54)	0.176	0.84 (0.14–5.09)	0.854
PT-A	0.92 (0.81–1.03)	0.172	0.99 (0.85–1.15)	0.865
INR	1.00 (0.93–1.07)	0.950	1.01 (0.92–1.11)	0.801
APTT (S)	1.01 (0.96–1.05)	0.751	0.99 (0.93–1.05)	0.724
FIB	1.00 (1.00–1.00)	0.665	1.00 (1.00–1.01)	0.222
FDP	0.98 (0.84–1.14)	0.783	0.94 (0.76–1.15)	0.528
D-dimer	1.00 (1.00–1.00)	0.681	1.00 (1.00–1.00)	0.474

Model 1: patient- and laboratory-related factors; Model 2: laboratory-related factors.

*p < 0.05, **p < 0.01. Body mass index (BMI), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), white blood cell count (WBC), neutrophil ratio (Neu%), hemoglobin (Hb), platelet count (PLT), total protein (TP), albumin level (ALB), alanine aminotransferase (ALT), aspartate aminotransferase (AST), creatinine (Cr), international normalized ratios (INR), fibrin degradation product (FDP), activated partial thromboplastin time (APTT), D-dimer, fibrinogen (Fib), prothrombin time (PT), and plasma thromboplastin antecedent (PT-A).