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. 2021 Oct 29;12:755866. doi: 10.3389/fimmu.2021.755866

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Copyright © 2021 Que, Xu, Xu, Almeida, Zhu, Wang, Wang, Liu, Jiang, Wang, Li and Zhou

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of time to recovery of neutrophil, cytokine release syndrome (CRS), and inflammatory factors between EMM patients and non-EMM patients receiving anti-BCMA CAR-T cell therapy in two clinical trials conducted in our center (A) Time to the recovery of patients with grade 3/4 neutropenia is shown. One non-EMM patient was excluded because the neutrophil count had not recovered until death (OS = 20 days). Time to recovery, which is defined as absolute neutrophil count ≥1000 cells/μL from infusion till the first time of recovery. (B–D) Comparison of the CRS grade, the peak levels of IL-6 and Ferritin.