Table 4. Linear regression analyses for factors associated with the enlarged perivascular space scores.
| Total ePVS score | B (95% CI) | P |
| Age (year) | 0.069 (0.029–0.108) | 0.001** |
| Apnea-hypopnea index (/h) | 0.024 (0.003–0.045) | 0.026* |
| MCA PI | 2.556 (-0.441–5.554) | 0.095 |
| MRIR | 10.264 (3.183–17.346) | 0.020* |
| Thresholds | B (SE) | |
| 0 | 18.388 (4.206) | |
| 1 | 19.487 (4.227) | |
| 2 | 20.846 (4.282) | |
| 3 | 21.631 (4.317) | |
| 4 | 23.128 (4.383) | |
| 5 | 25.197 (4.481) | |
| CS ePVS score | B (95% CI) | P |
| Age (year) | 0.061 (0.020–0.103) | 0.004** |
| Apnea-hypopnea index (/h) | 0.026 (0.004–0.048) | 0.019* |
| MCA PI | 2.753 (-0.363–5.868) | 0.083 |
| MRIR | 7.264 (2.183–12.345) | 0.036* |
| Thresholds | B (SE) | |
| 0 | 13.385 (4.324) | |
| 1 | 14.946 (4.367) | |
| 2 | 16.833 (4.434) | |
| 3 | 19.793 (4.554) | |
| BG ePVS score | B (95% CI) | P |
| Age (year) | 0.062 (0.016–0.108) | 0.008** |
| Respiratory distress index (/h) | 0.022 (-0.001–0.045) | 0.060 |
| MCA PI | 2.137 (-1.183–5.458) | 0.207 |
| MRIR | 9.764 (2.967–16.373) | 0.031* |
| Hypertension | 1.602 (0.652–2.551) | 0.001** |
| Thresholds | B (SE) | |
| 0 | 19.491 (4.88) | |
| 1 | 23.079 (5.082) | |
| 2 | 26.434 (5.263) |
aR2 = 0.388 and P<0.001, bR2 = 0.384 and P = 0.001, and cR2 = 0.378 and P<0.001 for the regression equation.
B: unstandardized coefficient, CI: confidence interval, ePVS: enlarged perivascular space, CS: centrum semiovale, BG: basal ganglia, MCA: middle cerebral artery, PI: pulsatility index, and MRIR: mean middle cerebral artery resistance index ratio.
*P<0.05 and
**P<0.01.