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. Author manuscript; available in PMC: 2022 Aug 20.
Published in final edited form as: ACS Catal. 2021 Aug 5;11(16):10351–10361. doi: 10.1021/acscatal.1c03092

Figure 8.

Figure 8.

Quantifying the effect of reaction parameters on yields of five major products of the reaction. (A) Mathematical model for finding the pseudoinverse of a conditions matrix and how the unknown parameters relate the condition matrix to the yield matrix. (B) Plot of quantitative contributions of 18 reaction parameters (one was discarded in the analysis) on yields of five analytes. The yield of anti-spiroindane is higher if the overall concentration is kept low, if there is more catalyst, and reducing agent, and if triethylborane is the Lewis acid and toluene the solvent.