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. 2021 Nov 12;7(46):eabk0271. doi: 10.1126/sciadv.abk0271

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Fig. 6. — (A) Mitochondrial concentration [intensity (a.u.)/volume (fl) in XS, M, and XL HSCs (n = 4)]. (B) ROS concentration dichlorodihydrofluorescein diacetate (DCF-DA) intensity (a.u.)/volume (fl) in XS, M, and XL HSCs (n = 4). (C) Heatmap of expression levels of mitochondrial genes in differently sized G_0/1 HSCs (n = 2). (D) Metabolites were analyzed using liquid chromatography–tandem mass spectrometry: Volcano plots of metabolite changes induced by in G_0/1 XL HSCs compared to G_0/1 XS HSCs. Red/blue circles show metabolites significantly depressed/elevated, and symbols in black show unchanged metabolites (n = 7). NAD⁺, nicotinamide adenine dinucleotide. NAM, Nicotinamide.