Table 1.
Demographic and clinical characteristics of study subjects
|
Healthy (16) |
Moderate/severe (30) |
Critical (14) |
p | |
|---|---|---|---|---|
| Age (years) | 38.19 (8.81) | 58.33 (18.49) | 52.64 (17.83) | |
| Gender | ||||
| Female | 5 | 14 | 6 | |
| Male | 11 | 16 | 8 | |
| Temperature | 36.56 (0.108) | 37.41 (1.007) | 37.41 (0.401) | <.0001 |
| Cough | 0 (0%) | 23 (76%) | 12 (85%) | <.0001 |
| Smoking | 1 (0.06%) | 4 (0.13%) | 0 (0%) | .3555 |
| chronic underlying disease | 0 | 12 (40%) | 10 (71%) | .0006 |
| LDH (U/L) | 251.9 (80.86) | 556.4 (268.5) | 1863 (2709) | <.0001 |
| C‐reactive protein (mg/dl) | 1.746 (1.563) | 81.97 (68.83) | 191.3 (116.6) | <.0001 |
| ESR (mm/h) | 10.71 (3.989) | 61.21 (45.62) | 69.58 (32.49) | <.0001 |
| Ferritin (ng/ml) | 102.9 (51.98) | 689.6 (731.9) | 1129 (1071) | .0002 |
| BUN (mg/dl) | 15.00 (3.486) | 21.35 (19.54) | 39.54(27.20) | .0005 |
| Creatinine (mg/dl) | 0.8143 (0.1076) | 1.993 (2.764) | 2.106 (2.114) | .0673 |
| AST (IU/L) | 21.36 (3.875) | 51.57 (65.96) | 120.3 (201.5) | .0100 |
| ALT (IU/L) | 18.00 (6.493) | 39.33 (27.49) | 180.5 (333.9) | .0171 |
| WBC | 7490 (1798) | 8243 (3631) | 9407 (3693) | .2949 |
| Lymphocytes (% in differential) | 32.19 (4.324) | 23.43 (12.01) | 12.29 (5.121) | <.0001 |
| Lymphocytes (absolute number) | 2384 (534.7) | 1825 (1130) | 1069 (409.9) | <.0001 |
| Neutrophil (% in differential) | 67.20 (10.11) | 70.07 (11.92) | 84.21 (8.059) | .0002 |
| Neutrophil (absolute number) | 5059 (1530) | 5897 (3048) | 8036 (3595) | .0234 |
| PLT | 269,267 (103,425) | 267,467 (137,550) | 211,429 (132,324) | .3101 |
| NLR | 2.159 (0.5858) | 3.98 (2.308) | 8.571 (4.927) | <.0001 |
| PLR | 114.2 (39.30) | 184.4 (108.1) | 207.2 (125.9) | .0308 |
| Hb (mg/dl) | 14.58 (1.546) | 11.06 (1.284) | 10.45 (1.599) | <.0001 |
Abbreviations: ALT, alanine aminotransferease; AST, aspartate aminotransferase; BUN, blood urea nitrogen; ESR, erythrocyte sedimentation rate; LDH, lactate dehydrogenase; NLR, neutrophil‐lymphocyte ratio; PLR, platelet‐lymphocyte ratio; PLT, platelet; WBC, white blood cell.