Table 1.
Demographic characteristics of mothers and HIV‐unexposed uninfected or HIV‐exposed uninfected newborns
| HUU (n = 25) | HEU (n = 50) | p Value a | |
|---|---|---|---|
| Maternal characteristics | |||
| Maternal age (years, mean ± SD) | 31.4 (5.3) | 26.7 (6.1) | 0.0028** |
| Number of prior pregnancies (mean±SD) | 2.8 (1.1) | 2.4 (1.2) | 0.2599 |
| CD4 count (cells/mm3) (mean ± SD) | ‐ | 1061 (377.8) | ‐ |
| Percentages of Th cells b (mean±SD) | 45.46 (6.4) | 29.4 (13.8) | <0.0001**** |
| Viral load (copies/ml), n (%) | ‐ | <200: 35 (70) | ‐ |
| 200–1000: 2 (4) | |||
| >1000: 9 (18) | |||
| Not sample: 4 (8) | |||
| Antiretrovirals, n (%) | ‐ | Integrase INH: 21(42) | ‐ |
| Protease INH: 18 (36) | |||
| Retrotranscriptase INH: 9 (18) | |||
| Unknown: 2 (4) | |||
| Newborn characteristics | |||
| Gestational age (weeks) (mean ± SD) | 38.6 (1.1) | 37.7 (1.8) | 0.0248* |
| Birth weight (g) (mean ± SD) | 2979 (374.9) | 2815 (420.1) | 0.0619 |
| Cephalic perimeter (cm) (mean ± SD) | 34.3 (1.3) | 33.6 (1.5) | 0.0423* |
| Length at birth (cm) (mean ± SD) | 48.4 (2.2) | 48.2 (2.2) | 0.5160 |
| CD4 count (cells/mm3) (mean ± SD) | ‐ | 2214 (943.3) | ‐ |
| Percentages of Th cells b (mean ± SD) | 66.01 (8.7) | 65.9 (11.8) | 0.9429 |
| Percentages of memory CD4+ T cells (CD45RA‐) (mean ± SD) | 14.35 (5.5) | 11.35 (7.1) | 0.0966 |
Abbreviations: HEU, HIV‐exposed uninfected newborn; HUU, HIV‐unexposed uninfected newborn; INH, inhibitor; n, number; SD, standard deviation.
a
All p values were calculated by the Mann–Whitney test.
b
Percentages of Th cells among total lymphocytes from peripheral blood.
* p < 0.05
** p < 0.01
**** p < 0.0001.