Table 1. Residues forming the HLA class I molecule pockets.

Pocket	Residues	Role of the pocket
A	5, 7, 59, 63, 66, 159, 163, 167, 171	Wall of the N-terminal part of the binding cleft, bind P1 residue
B	7, 9, 24, 34, 45, 63, 66, 67, 70, 99	Bind primary anchor residue P2
C	9, 70, 73, 74, 97	Bind secondary anchor residue at P3 and P5/P6 when presents, face pocket D
D	99, 114, 155, 156, 159, 160	Bind secondary anchor residue at P3 and P5/P6 when presents, face pocket C
E	97, 114, 147, 152, 156	Overlap with C/D pockets and contact secondary anchor residue at P5/P6 when presents and the C-terminal part of the peptide
F	77, 80, 81, 84, 95, 123, 143, 146, 147	Bind primary anchor residue PΩ, wall of the C-terminal part of the binding cleft