Table 2. Gene clusters.
| gene_id | Relative FC D32 sham vs CLP | p_value_ | Cluster # |
|---|---|---|---|
| Cdc6 | 4.03064298 | 0.00005 | Cluster 1 |
| Tppp3 | 4.88825654 | 0.00005 | Cluster 1 |
| Neil3 | 3.66496647 | 0.00005 | Cluster 1 |
| Hist1h1e | 3.76231332 | 0.00005 | Cluster 1 |
| Mcm10 | 3.47460746 | 0.00005 | Cluster 1 |
| Ttc8 | 3.38918878 | 0.00005 | Cluster 1 |
| Stmn1 | 2.06406728 | 0.0508 | Cluster 1 |
| Gpr34 | 3.41697573 | 0.00005 | Cluster 1 |
| Ppp2r2c | 1.83454208 | 0.0437 | Cluster 1 |
| Kntc1 | 2.99415727 | 0.00005 | Cluster 1 |
| Bfsp1 | 1.60516322 | 0.03045 | Cluster 1 |
| Birc5 | 2.8137029 | 0.00005 | Cluster 1 |
| Ccdc136 | 2.28917856 | 0.0344 | Cluster 1 |
| Gm5124 | 1.60472157 | 0.03095 | Cluster 1 |
| Ccnb2 | 2.49461988 | 0.00005 | Cluster 1 |
| Apol7b | 2.6692603 | 0.00005 | Cluster 1 |
| Tktl1 | 1.9334132 | 0.02895 | Cluster 1 |
| Dtl | 2.59828557 | 0.00005 | Cluster 1 |
| Pask | 2.7640812 | 0.00005 | Cluster 1 |
| Crip2 | 2.52029044 | 0.0004 | Cluster 1 |
| Clspn | 2.45116907 | 0.00015 | Cluster 1 |
| Mki67 | 2.61164716 | 0.00005 | Cluster 1 |
| Fam64a | 2.65731637 | 0.0006 | Cluster 1 |
| 2810408I11Rik | 1.5215239 | 0.06725 | Cluster 1 |
| Rad51ap1 | 1.63064417 | 0.00235 | Cluster 1 |
| Tnfsf4 | 2.37518519 | 0.0009 | Cluster 1 |
| E2f1 | 2.34354094 | 0.031 | Cluster 1 |
| Cep55 | 2.4930123 | 0.0004 | Cluster 1 |
| Morn3 | 2.12074329 | 0.00035 | Cluster 1 |
| Aurkb | 2.4030389 | 0.00005 | Cluster 1 |
| Hist2h2bb | 2.02820011 | 0.0464 | Cluster 1 |
| Exo1 | 2.36813282 | 0.00005 | Cluster 1 |
| Fcrlb | 1.52457593 | 0.04225 | Cluster 1 |
| Tmem176a | 1.59714799 | 0.0361 | Cluster 1 |
| Socs2 | 2.02128114 | 0.00155 | Cluster 1 |
| Ncapg2 | 1.97320931 | 0.00745 | Cluster 1 |
| Klra9 | 2.11296665 | 0.00005 | Cluster 1 |
| Chek1 | 1.59507471 | 0.05475 | Cluster 1 |
| Rad51 | 1.58587164 | 0.00005 | Cluster 1 |
| Dscc1 | 1.74867599 | 0.00015 | Cluster 1 |
| Bzrap1 | 1.61419626 | 0.00005 | Cluster 1 |
| Cd300e | 1.519849 | 0.07755 | Cluster 1 |
| Gm1720 | 1.94574412 | 0.0019 | Cluster 1 |
| Brca1 | 1.5604888 | 0.05435 | Cluster 1 |
| Gm14124 | 1.64708499 | 0.03685 | Cluster 1 |
| Shcbp1 | 1.79205262 | 0.00005 | Cluster 1 |
| Nebl | 1.8053468 | 0.04325 | Cluster 1 |
| Ckap2l | 1.73019782 | 0.0003 | Cluster 1 |
| Cdkn2a | 1.82961741 | 0.00085 | Cluster 1 |
| Phlda3 | 1.63185741 | 0.03825 | Cluster 1 |
| Adgre4 | 1.57646266 | 0.00005 | Cluster 1 |
| Klri2 | 1.56007674 | 0.0011 | Cluster 1 |
| Mmp25 | 1.54571785 | 0.04745 | Cluster 1 |
| Nenf | 1.5307705 | 0.0182 | Cluster 1 |
| Igf1 | –1.524316 | 0.01 | Cluster 1 |
| Rac3 | –1.5034855 | 0.07065 | Cluster 1 |
| Trf | –1.6496992 | 0.00015 | Cluster 1 |
| Chaf1a | –1.6002474 | 0.0011 | Cluster 1 |
| Orc1 | –1.6245667 | 0.04185 | Cluster 1 |
| Fignl1 | –1.7257028 | 0.0216 | Cluster 1 |
| D430020J02Rik | –1.6263897 | 0.0051 | Cluster 1 |
| Cenph | –1.8078839 | 0.0047 | Cluster 1 |
| Blvrb | –1.8434164 | 0.0457 | Cluster 1 |
| Cpne7 | –1.5149666 | 0.02655 | Cluster 1 |
| Psrc1 | –1.7535019 | 0.00145 | Cluster 1 |
| Uhrf1 | –1.5739852 | 0.0013 | Cluster 1 |
| Plbd1 | –1.7851892 | 0.0021 | Cluster 1 |
| Rgs12 | –1.8455643 | 0.01885 | Cluster 1 |
| Hpgd | –1.8522078 | 0.06025 | Cluster 1 |
| P2r×7 | –2.0648257 | 0.01595 | Cluster 1 |
| Bub1b | –2.2247142 | 0.0223 | Cluster 1 |
| 4833418N02Rik | –2.3048295 | 0.011 | Cluster 1 |
| Ube2c | –1.621509 | 0.0124 | Cluster 1 |
| Cadm1 | –2.3409109 | 0.00015 | Cluster 1 |
| Tyrobp | –2.4355709 | 0.00335 | Cluster 1 |
| Jup | –2.4842838 | 0.0023 | Cluster 1 |
| Pyroxd2 | –2.2264265 | 0.0282 | Cluster 1 |
| Gins1 | –1.8339216 | 0.00005 | Cluster 1 |
| Gm4013 | –2.7505116 | 0.01255 | Cluster 1 |
| Axl | –2.6625156 | 0.00005 | Cluster 1 |
| Nr6a1 | –2.729109 | 0.00125 | Cluster 1 |
| Hspa2 | –2.796573 | 0.00005 | Cluster 1 |
| Spry2 | –2.7405966 | 0.00005 | Cluster 1 |
| Mpeg1 | –2.8281527 | 0.00005 | Cluster 1 |
| Ticrr | –2.9418017 | 0.00005 | Cluster 1 |
| Plxdc1 | –2.9468017 | 0.00005 | Cluster 1 |
| Ly86 | –3.2898687 | 0.0019 | Cluster 1 |
| Cd302 | –3.3417875 | 0.00005 | Cluster 1 |
| C6 | –3.3367417 | 0.0003 | Cluster 1 |
| Slc37a2 | –3.3489759 | 0.00005 | Cluster 1 |
| Gm2011 | –3.4732831 | 0.00005 | Cluster 1 |
| H2-T3 | –2.0828371 | 0.00935 | Cluster 1 |
| Wnt2b | –3.5079301 | 0.0004 | Cluster 1 |
| Clec12a | –3.0562022 | 0.00895 | Cluster 1 |
| Mmp17 | –4.1251312 | 0.00005 | Cluster 1 |
| Ncaph | –4.1603359 | 0.0417 | Cluster 1 |
| Kcnj10 | –4.2878368 | 0.00005 | Cluster 1 |
| Cd163 | –4.2866184 | 0.0001 | Cluster 1 |
| Il11 | –5.666901 | 0.0001 | Cluster 1 |
| Syk | 4.80557812 | 0.0603 | Cluster 2 |
| 9030619P08Rik | 2.73623094 | 0.0353 | Cluster 2 |
| Prss16 | 2.57604894 | 0.00005 | Cluster 2 |
| Tcf4 | 2.52783097 | 0.0069 | Cluster 2 |
| Itgad | 2.32061951 | 0.00005 | Cluster 2 |
| Abcc3 | 2.47441931 | 0.0143 | Cluster 2 |
| Hfe | 1.91152093 | 0.00065 | Cluster 2 |
| Fcgr3 | 1.94948898 | 0.00005 | Cluster 2 |
| Rab3il1 | 2.00253853 | 0.00255 | Cluster 2 |
| Lrp1 | 2.06172226 | 0.06585 | Cluster 2 |
| Cd5l | 1.6117422 | 0.0645 | Cluster 2 |
| Mir2861 | 1.93355795 | 0.0162 | Cluster 2 |
| Il18 | 1.64165162 | 0.07875 | Cluster 2 |
| Mir155hg | 1.9632828 | 0.0003 | Cluster 2 |
| Irf4 | 1.83011207 | 0.00085 | Cluster 2 |
| Cmklr1 | 1.71253206 | 0.00655 | Cluster 2 |
| Mt3 | 1.61299839 | 0.00005 | Cluster 2 |
| Cd163l1 | 1.68200967 | 0.0028 | Cluster 2 |
| Palm | 1.69858804 | 0.0309 | Cluster 2 |
| Hmox1 | 1.8719138 | 0.0014 | Cluster 2 |
| Mertk | 1.69725108 | 0.05425 | Cluster 2 |
| Esm1 | 1.55538421 | 0.08875 | Cluster 2 |
| Lrrc25 | 1.53588266 | 0.01125 | Cluster 2 |
| Lgmn | 1.53366352 | 0.0421 | Cluster 2 |
| Mafb | 1.59909428 | 0.00005 | Cluster 2 |
| Havcr2 | 1.61859719 | 0.00005 | Cluster 2 |
| Epb4.1l3 | 1.64271249 | 0.0257 | Cluster 2 |
| Siglece | 1.58382507 | 0.0091 | Cluster 2 |
| Prr5 | –1.5418463 | 0.05615 | Cluster 2 |
| Pla2g7 | –1.5675528 | 0.00005 | Cluster 2 |
| Dusp14 | –1.6724627 | 0.02015 | Cluster 2 |
| Tgm2 | –1.6678575 | 0.04595 | Cluster 2 |
| Riiad1 | –1.5429946 | 0.00005 | Cluster 2 |
| Lilrb4a | –1.6883324 | 0.00685 | Cluster 2 |
| Ninj2 | –1.5669531 | 0.08315 | Cluster 2 |
| Cish | –1.6443416 | 0.0508 | Cluster 2 |
| Cenpe | –1.8650444 | 0.07995 | Cluster 2 |
| Cenpm | –1.5922104 | 0.00155 | Cluster 2 |
| Tpx2 | –1.5558403 | 0.05695 | Cluster 2 |
| Oip5 | –1.7861225 | 0.00005 | Cluster 2 |
| Cdca7 | –1.5875434 | 0.04035 | Cluster 2 |
| Ckap2 | –1.6603956 | 0.00425 | Cluster 2 |
| Ncapg | –1.8932803 | 0.019 | Cluster 2 |
| Ssc4d | –1.9973193 | 0.0063 | Cluster 2 |
| Stkld1 | –1.8746276 | 0.04135 | Cluster 2 |
| Cdca8 | –1.6650517 | 0.0087 | Cluster 2 |
| Cdc45 | –1.9715619 | 0.00405 | Cluster 2 |
| Lrp11 | –1.9542283 | 0.0003 | Cluster 2 |
| Mcm5 | –1.965633 | 0.012 | Cluster 2 |
| Cks1b | –2.0197826 | 0.0137 | Cluster 2 |
| Apitd1 | –1.614175 | 0.01045 | Cluster 2 |
| Spc24 | –2.1192151 | 0.00145 | Cluster 2 |
| Serpine2 | –2.0231734 | 0.00005 | Cluster 2 |
| Brip1 | –1.6461742 | 0.092 | Cluster 2 |
| Pole | –2.2240204 | 0.0253 | Cluster 2 |
| Lig1 | –1.7583399 | 0.0015 | Cluster 2 |
| Cenpn | –1.7057202 | 0.00005 | Cluster 2 |
| Gm19434 | –2.012432 | 0.0005 | Cluster 2 |
| Carns1 | –2.0274411 | 0.0205 | Cluster 2 |
| Mpp2 | –1.5418367 | 0.00775 | Cluster 2 |
| Mustn1 | –2.061708 | 0.0017 | Cluster 2 |
| Rn45s | –2.10963 | 0.07705 | Cluster 2 |
| Sema6b | –2.2547383 | 0.0119 | Cluster 2 |
| Cfp | –2.0456935 | 0.0001 | Cluster 2 |
| App | –2.211262 | 0.00935 | Cluster 2 |
| Car9 | –2.0062063 | 0.02255 | Cluster 2 |
| 1700102P08Rik | –2.4325509 | 0.0268 | Cluster 2 |
| Snhg10 | –2.345361 | 0.00015 | Cluster 2 |
| Lima1 | –2.3391753 | 0.07585 | Cluster 2 |
| Selm | –2.0294095 | 0.00265 | Cluster 2 |
| Slc41a3 | –2.1887998 | 0.0001 | Cluster 2 |
| Src | –2.6392902 | 0.00015 | Cluster 2 |
| Miat | –2.5487856 | 0.0109 | Cluster 2 |
| Cd79a | –2.5900501 | 0.00055 | Cluster 2 |
| Plxnb2 | –2.9874612 | 0.00005 | Cluster 2 |
| Pla2g2d | –1.529167 | 0.0268 | Cluster 2 |
| Lyz2 | –2.9362402 | 0.04775 | Cluster 2 |
| Cdk3-ps | –3.0692156 | 0.00265 | Cluster 2 |
| Mir6236 | –2.5029162 | 0.0004 | Cluster 2 |
| Smagp | –1.9662967 | 0.00005 | Cluster 2 |
| AF251705 | –2.8636993 | 0.0226 | Cluster 2 |
| Gfra2 | –2.8780666 | 0.00005 | Cluster 2 |
| Tmem91 | –3.2171875 | 0.00005 | Cluster 2 |
| Pld4 | –1.5079912 | 0.02785 | Cluster 2 |
| Itgb5 | –1.6713455 | 0.00225 | Cluster 2 |
| Treml4 | –3.2826024 | 0.0001 | Cluster 2 |
| Cd14 | –2.7112347 | 0.00005 | Cluster 2 |
| Marcks | –3.1963602 | 0.00005 | Cluster 2 |
| Cmbl | –2.6693158 | 0.00005 | Cluster 2 |
| Klra3 | –2.5417462 | 0.03455 | Cluster 2 |
| Ctsh | –3.5891694 | 0.00565 | Cluster 2 |
| Klra8 | –3.3087585 | 0.0001 | Cluster 2 |
| Cd81 | –3.3276415 | 0.00005 | Cluster 2 |
| C1qb | –3.7316146 | 0.00005 | Cluster 2 |
| Aif1 | –3.2695906 | 0.01525 | Cluster 2 |
| Bank1 | –3.0876517 | 0.002 | Cluster 2 |
| C1qc | –3.0727492 | 0.0001 | Cluster 2 |
| Apoe | –3.5282676 | 0.00005 | Cluster 2 |
| Clec4a3 | –2.9215824 | 0.00015 | Cluster 2 |
| Tgfbi | –3.5641054 | 0.00005 | Cluster 2 |
| Mrc1 | –3.6479097 | 0.03025 | Cluster 2 |
| Sirpa | –4.0829446 | 0.00005 | Cluster 2 |
| Clec1b | –1.7537681 | 0.0004 | Cluster 2 |
| Klra14-ps | –3.8984753 | 0.00005 | Cluster 2 |
| Ccr3 | –2.5323907 | 0.06515 | Cluster 2 |
| C1qa | –3.5880749 | 0.00005 | Cluster 2 |
| Vcam1 | –3.6726209 | 0.0011 | Cluster 2 |
| Tbxas1 | –4.4023688 | 0.00005 | Cluster 2 |
| Csf1r | –4.0805398 | 0.00005 | Cluster 2 |
| Fcna | –3.3668046 | 0.00005 | Cluster 2 |
| Adgre1 | –3.7926073 | 0.00005 | Cluster 2 |
| Adamdec1 | –4.9789792 | 0.00005 | Cluster 2 |
| Tnfrsf8 | –2.2700751 | 0.0008 | Cluster 2 |
| Aldh2 | 2.4260512 | 0.00025 | Cluster 3 |
| Slc40a1 | 2.40044187 | 0.0057 | Cluster 3 |
| Zfp385a | 2.16534965 | 0.06435 | Cluster 3 |
| Spag5 | 1.88610893 | 0.00005 | Cluster 3 |
| Nusap1 | 1.84390075 | 0.09965 | Cluster 3 |
| B9d1 | 1.78604818 | 0.0031 | Cluster 3 |
| Top2a | 1.74249558 | 0.0044 | Cluster 3 |
| Alox5ap | 1.64982614 | 0.09075 | Cluster 3 |
| Sgol2a | 1.61420186 | 0.05365 | Cluster 3 |
| Cdk1 | 1.59276453 | 0.0489 | Cluster 3 |
| Pla2g4b | 1.58954405 | 0.04465 | Cluster 3 |
| Fam174b | 1.54600394 | 0.00895 | Cluster 3 |
| Spc25 | 1.51665085 | 0.0962 | Cluster 3 |
| Ppp1r13l | –1.5091602 | 0.0399 | Cluster 3 |
| Neto2 | –1.5160875 | 0.0106 | Cluster 3 |
| Eif3j2 | –1.5188243 | 0.03625 | Cluster 3 |
| Gm28042 | –1.5257346 | 0.02945 | Cluster 3 |
| Gm4532 | –1.5651414 | 0.05395 | Cluster 3 |
| Sowahc | –1.5972355 | 0.09105 | Cluster 3 |
| Tnfrsf21 | –1.6215854 | 0.04005 | Cluster 3 |
| Gm3435 | –1.6321142 | 0.01435 | Cluster 3 |
| Zfp112 | –1.6371301 | 0.04985 | Cluster 3 |
| Nr1h3 | –1.6602966 | 0.07725 | Cluster 3 |
| 2810468N07Rik | –1.6797191 | 0.0173 | Cluster 3 |
| Hck | –1.6894024 | 0.04875 | Cluster 3 |
| Pth1r | –1.7203976 | 0.06865 | Cluster 3 |
| Tagln3 | –1.7598763 | 0.05825 | Cluster 3 |
| Hist1h4d | –1.7606181 | 0.0688 | Cluster 3 |
| Tubb3 | –1.803737 | 0.00005 | Cluster 3 |
| Klre1 | –1.8122236 | 0.02795 | Cluster 3 |
| Spi1 | –1.8248628 | 0.0498 | Cluster 3 |
| Fcgr4 | –1.8961012 | 0.01005 | Cluster 3 |
| Mrgpre | –1.9259777 | 0.00455 | Cluster 3 |
| Chrne | –1.9429018 | 0.03985 | Cluster 3 |
| Tctex1d2 | –1.9516374 | 0.00005 | Cluster 3 |
| Sdc3 | –1.9572554 | 0.0026 | Cluster 3 |
| Tlr7 | –1.9874423 | 0.0019 | Cluster 3 |
| Slc11a1 | –2.0856253 | 0.001 | Cluster 3 |
| Gzma | –2.102273 | 0.00005 | Cluster 3 |
| Cpsf4l | –2.1529279 | 0.0146 | Cluster 3 |
| Clec4a1 | –2.2106337 | 0.0132 | Cluster 3 |
| Fcer1g | –2.2631622 | 0.0002 | Cluster 3 |
| Ncf2 | –2.2765987 | 0.00205 | Cluster 3 |
| Slpi | –2.2838533 | 0.00005 | Cluster 3 |
| Cd244 | –2.4303599 | 0.0011 | Cluster 3 |
| Ptgs1 | –2.5181601 | 0.0003 | Cluster 3 |
| Cybb | –2.7556258 | 0.0001 | Cluster 3 |
| Matk | –3.0595087 | 0.00005 | Cluster 3 |
| Ifitm2 | –3.1387932 | 0.01575 | Cluster 3 |
| Cdc20b | –3.2338662 | 0.00705 | Cluster 3 |
| Msc | –3.4433671 | 0.01 | Cluster 3 |
| Clec4n | –3.4851723 | 0.00015 | Cluster 3 |
| Rgl1 | –3.5597601 | 0.0001 | Cluster 3 |
| Spic | –3.6767727 | 0.00005 | Cluster 3 |
| Hebp1 | –3.7616875 | 0.00025 | Cluster 3 |
| Hist1h3e | –4.1043962 | 0.04245 | Cluster 3 |
| Lrg1 | –5.383073 | 0.0033 | Cluster 3 |