Table 1.
Patient Characteristics and Hyperfibrinolysis Cutoffs Predictive of Massive Transfusion at Three Level 1 Trauma Centers
| Characteristics |
Center 1
N=332 |
Center 2
N=893 |
Center 3
N=922 |
P-value |
|---|---|---|---|---|
| Age in years, Median (IQR) | 35 (26–50) | 37 (26–52) | 36 (25–49) | 0.03 |
| ISS, Median (IQR) | 26 (15–36) | 22 (18–29) | 13 (4–27) | <0.0001 |
| Blunt Injury, N (%) | 173 (52.1%) | 689 (77.2%) | 472 (51.2%) | <0.0001 |
| Admission SBP (mmHg) Median (IQR) | 93(76–120) | 110 (90–130) | 122 (100–140) | <0.0001 |
| Massive Transfusion, N (%) | 75 (22.6%) | 108 (12.1%) | 93 (10.1%) | <0.0001 |
| In Hospital Mortality, N (%) | 85 (25.6%) | 92 (10.3%) | 116 (12.6%) | <0.0001 |
| Hyperfibrinolysis Cutoffs, LY30% | |||
|---|---|---|---|
| All Patients | 11.5 | 5.0 | 7.0 |
| By Admission SBP, mmHg | |||
| >90 | 13.9 | 5.1 | 8.7 |
| 70–90 | 7.7 | 2.9 | 7.0 |
| <70 | 2.5 | 2.2 | 3.7 |
| By Injury Severity Score | |||
| <26 | 11.5 | 5.0 | 7.0 |
| 26–50 | 2.6 | 5.1 | 1.8 |
| >50 | 2.5 | 1.0 | 1.9 |
ISS: Injury Severity Score; SBP: Systolic Blood Pressure; IQR: interquartile range