Table 1.

GO and KEGG pathway analysis results for differentially expressed RBPs in 3 critical modules.

MCODE	Processes or pathways	P value
GO
Module 1	Ribosome biogenesis	3.60E-79
	rRNA metabolic process	7.92E-78
	rRNA processing	1.56E-76
	ncRNA processing	2.71E-73
	Preribosome	1.39E-57
Module 2	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	2.30E-28
	mRNA splicing, via spliceosome	2.30E-28
	RNA splicing, via transesterification reactions	2.70E-28
	RNA splicing	1.73E-26
	Catalytic step 2 spliceosome	3.34E-24
Module 3	Translation factor activity, RNA binding	5.06E-13
	Cytoplasmic translational initiation	6.34E-11
	Translational initiation	1.20E-10
	Cytoplasmic translation	1.56E-10
	Translation initiation factor activity	6.93E-10
KEGG
Module 1	Ribosome biogenesis in eukaryotes	2.89E-36
Module 2	Spliceosome	1.19E-15
	mRNA surveillance pathway	3.99E-09
	RNA transport	8.53E-06
Module 3	RNA transport	2.41E-13
	Legionellosis	0.003
	Leishmaniasis	0.005
	Spliceosome	0.02
	Ribosome	0.02