TABLE 1.
Genome search results showing putative biosynthetic clusters encoding known antimicrobial substances analyzed by antiSMASH bioinformatics tool.
Compound | Mol. wt. | Gene composition | Strain GI9 | Strain SKUDU10 | References | ||||
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Nucleotide sequence identity (%) | Region | Nucleotide seq (From to) | Nucleotide sequence identity (%) | Region | Nucleotide seq (From to) | ||||
Tyrocidine | 1270.5 | NRPS | 12 | NZ_CAGD010000017.2 | 52,248–99,261 | 12 | NZ_LSSO0100041.1 | 1–59,439 | Lipmann et al., 1941 |
Bogorol A | 1584 | NRPS | 100 | NZ_CAGD01000001.1 | 263,605–358,538 | 72 | NZ_LSSO0100074.1 | 1–59,851 | Dejong et al., 2016 |
Obafluorin | 358.3. | NRPS | 14 | NZ_CAGD01000004.1 | 1–96,545 | – | Scott et al., 2017 | ||
Tauramamide | 864 | NRPS | 36 | NZ_CAGD01000002.1 | 45,343–174,440 | 9 | NZ_LSSO0100061.1 | 1–21,011 | Dejong et al., 2016 |
Bacillibactin | 882.789 | NRPS | 15 | NZ_CAGD01000003.1 | 103,400–199,283 | – | Kunst et al., 1997 | ||
Brevicidine | 507 | NRPS | 100 | NZ_CAGD01000002.4 | 348,872–438,222 | 63 | NZ_LSSO0100085.1 | 1–56,502 | Li et al., 2018 |
Petrobactin | 718.8 | Siderophore | 100 | NZ_CAGD01000001.2 | 421,376–435,075 | 100 | NZ_LSSO0100071.1 | 7,913–21,612 | Cendrowski et al., 2004 |
Basiliskamide A/B | 385.5 | Polyketide | 90 | NZ_CAGD010000027.1 | 1–60,445 | 9 | NZ_LSSO01000152.1 | 1–6,065 | Theodore et al., 2014 |
Chejuenolide | 388.5 | NRPS and polyketide | 7 | NZ_CAGD01000002.2 | 177,888–247,190 | 7 | NZ_LSSO0100064.1 | 1–22,844 | Ng et al., 2018 |
Zwittermicin | 396.4 | NRPS and plyketide | 11 | NZ_CAGD010000017.1 | 184–49,900 | 44 | NZ_LSSO01000100.1 | 1–65,093 | Milner et al., 1996 |
Merosterol | 583.497 | Sterol/terpene | – | 10 | NZ_LSSO01000158.1 | 1–36,882 | Moosmann et al., 2017 |