Table 3.

Sensitivity analysis of hippocampal volume and asymmetry index.

Volume (mm3)
Predictor	Coefficient	Coeff SD	df	F	p value	R2	AIC
Step 1: model without IHI						0.47	9777.3
Group	−86.89	28.96	1, 355	13.72	<0.001
Hemisphere	234.31	14.83	1, 358	487.49	<0.001
ICV	0.00	0.00	1, 355	188.41	<0.001
Age	−0.25	1.13	1, 355	0.05	0.82
Sex	−30.62	36.47	1, 355	0.70	0.40
Group:Hemisphere	−27.64	19.95	1, 358	1.92	0.17
Step 2: model with IHI						0.49	9724.9
Group	−67.40	28.49	1, 357	10.74	0.001
Hemisphere	211.85	14.46	1, 385	342.62	<0.001
IHI	−43.57	6.10	1, 560	50.81	<0.001
ICV	1.37	0.10	1, 355	201.52	<0.001
Age	−0.28	1.11	1, 355	0.06	0.80
Sex	−29.66	35.85	1, 355	0.68	0.41
Group:Hemisphere	−40.10	19.06	1, 358	4.42	0.04

Asymmetry index (R > L)
Predictor	Coefficient	Coeff SD	df	F	p value	R2	AIC
Step 1: model without IHI						0.13	−1629.3
Group	−2.01E−02	7.99E−03	1, 355	0.54	0.46
Region	−6.65E−02	7.05E−03	1, 355	110.35	<0.001
ICV	3.52E−08	2.33E−08	1, 355	2.29	0.13
Age	−8.67E−04	2.68E−04	1, 355	10.48	0.001
Sex	−5.51E−03	8.63E−03	1, 355	0.41	0.52
Group:Region	3.07E−02	9.48E−03	1, 358	10.49	0.001
Step 2: model with IHI						0.17	−1646.2
Group	−2.53E−02	7.85E−02	1, 354	2.54	0.11
Region	−6.65E−02	7.05E−03	1, 358	110.35	<0.001
IHI	1.15E−02	2.09E−03	1, 354	30.52	<0.001
ICV	2.35E−08	2.24E−08	1, 354	1.10	0.30
Age	−8.65E−04	2.57E−04	1, 354	11.29	<0.001
Sex	−3.26E−03	8.30E−03	1, 354	0.15	0.69
Group:Region	3.07E−02	9.48E-03	1, 358	10.49	0.001

AIC Akaike information criterion, ICV intracranial volume, IHI incomplete hippocampal inversion.

Bolded values indicate signifance at p < 0.05 level.