Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Inhibition of FLAP by AZD5718 blocks the production of leukotriene B4 and the cysteinyl leukotrienes (leukotriene C4, leukotriene D4, and leukotriene E4). AA, arachidonic acid; cPLA2, cytoplasmic phospholipase A2; FLAP, 5-lipoxygenase activating protein; 5-LO, 5-lipoxygenase; LTA4, leukotriene A4; LTB4, leukotriene B4; LTC4, leukotriene C4; LTD4, leukotriene D4; LTE4, leukotriene E4.
