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. 2021 Sep 11;10:100179. doi: 10.1016/j.lanepe.2021.100179

Table 4.

Lung cancer incidence by baseline nodule category of subject (screening arm only).

Baseline nodule category Number (%) Lung cancers (incidence) Lung cancer detected at:
Baseline 3m FU 12m FU 1-2y 2-5y >5y
1 963 (49.3) 8 (0.8%) - - - 3 0 5
2 469 (24.0) 9 (1.9%) - - 1 1 3 4
3 458 (23.4) 32 (7.0%) - 2 7 0 14 9
4 64 (3.3) 35 (54.7%) 32 - - 2 1 0
All 1954 84* 32 2 8 6 18 18

UKLS Pulmonary Nodule categories described in Supplementary materials; Note: All subjects with Category 4 nodules investigated clinically after baseline; those with Category 3 nodules had follow up scan (FU) at 3 and 12 months (m); those with Category 2 nodules had FU at 12m; Category 1 subjects (nodules < Category 2 or no nodules detected) had no FU.

Data not available for 2 cancers diagnosed in CT screening arm as amongst the 34 subjects who did not receive a LDCT scan (one at 7 months and one at 5.7 years).