Table 4.
Lung cancer incidence by baseline nodule category of subject (screening arm only).
Baseline nodule category | Number (%) | Lung cancers (incidence) | Lung cancer detected at: |
|||||
---|---|---|---|---|---|---|---|---|
Baseline | 3m FU | 12m FU | 1-2y | 2-5y | >5y | |||
1 | 963 (49.3) | 8 (0.8%) | - | - | - | 3 | 0 | 5 |
2 | 469 (24.0) | 9 (1.9%) | - | - | 1 | 1 | 3 | 4 |
3 | 458 (23.4) | 32 (7.0%) | - | 2 | 7 | 0 | 14 | 9 |
4 | 64 (3.3) | 35 (54.7%) | 32 | - | - | 2 | 1 | 0 |
All | 1954 | 84* | 32 | 2 | 8 | 6 | 18 | 18 |
UKLS Pulmonary Nodule categories described in Supplementary materials; Note: All subjects with Category 4 nodules investigated clinically after baseline; those with Category 3 nodules had follow up scan (FU) at 3 and 12 months (m); those with Category 2 nodules had FU at 12m; Category 1 subjects (nodules < Category 2 or no nodules detected) had no FU.
Data not available for 2 cancers diagnosed in CT screening arm as amongst the 34 subjects who did not receive a LDCT scan (one at 7 months and one at 5.7 years).