Table 3.
Intraclass correlation coefficients (ICCs), standard error of measurement (SEM), and minimum detectable difference (MDD) values for interreader reliability and test-retest reliability
| Interreader ICC | Test-retest ICC | SEM | MDD | ||||
|---|---|---|---|---|---|---|---|
| Reader 1 | Reader 2 | Interreader | Test-retest | Interreader | Test-retest | ||
| MTR | 0.81 (0.60–0.92) | 0.79 (0.62–0.90) | 0.75 (0.55–0.88) | 1.7% | 1.7% | 4.7% | 4.7% |
| T2 | 0.92 (0.81–0.97) | 0.92 (0.84–0.96) | 0.9 (0.80–0.95) | 2.67 ms | 2.66 ms | 7.4 ms | 7.37 ms |
| PSD | 0.94 (0.85–0.98) | 0.94 (0.87–0.97) | 0.94 (0.88–0.97) | 21.3 | 20.1 | 59 | 55.7 |
| Normalized PSD | 0.89 (0.74–0.95) | 0.9 (0.81–0.96) | 0.89 (0.78–0.95) | 0.03 | 0.03 | 0.08 | 0.08 |
Intraclass correlation coefficients (ICCs) with 95% confidence-interval were calculated according to Shrout and Fleiss. SEM and MDD calculations were based on Popovic and Thomas [31]. MTR magnetization transfer ratio, T2 transverse relaxation time, PSD proton spin density