Table 2.

Diagnostic performance of qualitative assessment of vertebral compression fractures (VCF) for each reader

	AUC [95% CI]	Sensitivity (%) [95% CI]	Specificity (%) [95% CI]	+LR	−LR
Reader 1	0.99 [0.95, 1.00]	100.0 [89.1, 100.0] (32/32)	98.4 [91.5, 100.0] (62/63)	63.0 [9.0, 440.0]	0
Reader 2	0.99 [0.95, 1.00]	100.0 [89.1, 100.0] (32/32)	98.4 [91.5, 100.0] (62/63)	63.0 [9.0, 440.0]	0
Reader 3	0.97 [0.91, 0.99]	93.8 [79.2, 99.2] (30/32)	100.0 [94.3, 100.0] (63/63)	NA	0.06 [0.0, 0.2]
Reader 4	0.98 [0.92, 1.00]	100.0 [89.1, 100.0] (32/32)	95.2 [86.7, 99.0] (60/63)	21.0 [7.0, 63.4]	0

Two-by-two differences: no statistical difference between readers (all p > 0.29, Bonferroni corrected significance level p < 0.008)

AUC, area under the curve; 95% CI, 95% confidence intervals; +LR, positive likelihood ratio; −LR, negative likelihood ratio; NA, not applicable. Raw data are reported in parentheses wherever applicable