Table 1.
Patient and tumour characteristics of 246 patients with colon cancer
| Characteristics | All | Tumour-stroma ratio | Tumour budding | |||||
|---|---|---|---|---|---|---|---|---|
| Stroma-low (≤ 50%) |
Stroma-high (> 50%) |
Low (0–4 buds) |
Intermediate (5–9 buds) |
High (≥ 10 buds) |
||||
| N = 246 (%) | 137 (56) | 109 (44) | p-value | 194 (79) | 35 (14) | 17 (7) | p-value | |
| Age (years), mean (SD) | 68 (12) | 68 (12) | 67 (12) | 0.349 | 68 (12) | 65 (11) | 69 (13) | 0.282 |
| Gender | 0.166 | 0.456 | ||||||
| Male | 134 (54) | 80 (58) | 54 (50) | 109 (56) | 18 (51) | 7 (41) | ||
| Female | 112 (46) | 57 (42) | 55 (51) | 85 (44) | 17 (49) | 10 (59) | ||
| pTNM stage | 0.298 | 0.987 | ||||||
| II | 131 (53) | 77 (56) | 54 (50) | 104 (54) | 18 (51) | 9 (53) | ||
| III | 115 (47) | 60 (44) | 55 (51) | 90 (46) | 17 (49) | 8 (47) | ||
| pT status | 0.566 | 0.506 | ||||||
| T1 + T2 | 18 (7) | 17 (12) | 54 (50) | 17 (9) | 1 (3) | 0 (0) | ||
| T3 | 196 (80) | 106 (78) | 36 (33) | 152 (78) | 30 (86) | 14 (82) | ||
| T4 | 32 (13) | 14 (10) | 19 (17) | 25 (13) | 4 (11) | 3 (18) | ||
| pN status | 0.566 | 0.986 | ||||||
| N0 | 131 (53) | 77 (56) | 54 (50) | 104 (54) | 18 (51) | 9 (53) | ||
| N1 | 74 (30) | 38 (28) | 36 (33) | 59 (30) | 10 (29) | 5 (29) | ||
| N2 | 41 (17) | 22 (16) | 19 (17) | 31 (16) | 7 (20) | 3 (18) | ||
| Localisation | 0.002* | 0.859 | ||||||
| Right | 117 (48) | 77 (56) | 40 (37) | 93 (48) | 17 (49) | 7 (41) | ||
| Left | 129 (52) | 60 (44) | 69 (63) | 101 (52) | 18 (51) | 10 (59) | ||
| Adjuvant therapy | 0.553 | 0.106 | ||||||
| No | 154 (63) | 88 (64) | 66 (61) | 124 (64) | 17 (49) | 13 (77) | ||
| Yes | 92 (37) | 49 (36) | 43 (39) | 70 (36) | 18 (51) | 4 (24) | ||
*Significant result
N lymph nodes, p pathological, SD standard deviation, T tumour