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. 2021 Nov 12;11:22150. doi: 10.1038/s41598-021-00899-y

Table 2.

Empirical equilibrium concentrations of main small ions (in mOsm/L H2O) in human blood plasma (assumed protein equivalent: − 12.2 mEq/L) from Guyton and Hall17 and the associated equilibrium concentrations of ions in a protein-free fluid along with the theoretical values of the Gibbs–Donnan factor calculated using the presented method (eq. (16)).

Ion Empirical equilibrium concentrations: plasma Estimated equilibrium concentrations: protein-free fluid Estimated Gibbs–Donnan factor
Na+ 142.0 136.3 0.96
K+ 4.2 4.0 0.96
Ca2+ 1.3 1.2 0.92
Mg2+ 0.8 0.7 0.92
Cl 108.0 112.5 1.04
HCO3 24.0 25.0 1.04
Lactate 1.2 1.3 1.04
SO42− 0.5 0.5 1.09
HPO42− 2.0 2.2 1.09