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. 2021 Nov 12;11:22150. doi: 10.1038/s41598-021-00899-y

Table 3.

Estimated equilibrium concentrations of main small ions (in mOsm/L H2O) in human interstitial fluid (assumed protein equivalent: − 4.3 mEq/L)

taken from Table 1 and the equilibrium concentrations of ions in a protein-free fluid along with the theoretical values of the Gibbs–Donnan factor calculated using the presented method (eq. (16)).

Ion Estimated equilibrium concentrations: interstitial fluid Estimated equilibrium concentrations: protein-free fluid Estimated Gibbs–Donnan factor
Na+ 138.3 136.3 0.99
K+ 4.1 4.0 0.99
Ca2+ 1.2 1.2 0.97
Mg2+ 0.8 0.7 0.97
Cl 110.9 112.5 1.02
HCO3 24.7 25.0 1.02
Lactate 1.2 1.3 1.02
SO42− 0.5 0.5 1.03
HPO42− 2.1 2.2 1.03