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Indications for systemic treatment in sarcoidosis
| Symptoms impairing quality of life |
| Persistent lung infiltrates/decline in lung function at follow-up |
| Cardiac sarcoidosis |
| Neurological sarcoidosis |
| Ocular sarcoidosis not responding to topical therapy |
| Hypercalcaemia and/or hypercalciuria resistant to dietary vitamin D and calcium restrictions |
| Severe skin involvement with disfiguration (e.g. lupus pernio) |
| Other end organ failure |
