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. 2021 Aug 20;10(4):753–776. doi: 10.1007/s40123-021-00383-w

Table 3.

Patient characteristics

Parameter PRK LASIK SMILE p value
Eyes, n (%)
 R 17 (46) 177 (49) 7 (64)
 L 20 (54) 183 (51) 4 (36)
Age* (years) 34 ± 11 (18 to 57) 33 ± 8 (18 to 62) 28 ± 7 (23 to 43) 0.26
Sex, n (%)
 M 22 (71) 334 (51) 5 (71)
 F 9 (29) 316 (49) 2 (29)
Preoperative MRSE*a − 4.2 ± 3.8 (− 12.8 to 7.6) − 6.9 ± 5.6 (− 28.0 to 18.5) − 5.0 ± 2.7 (− 8.8 to − 2.0) 0.33
Preoperative anterior Km* (D) 43.7 ± 1.6 (39.7 to 46.1) 43.6 ± 1.8 (39.4 to 49.9) 43.6 ± 1.7 (40.9 to 45.3) 0.97

Preoperative

CCT*a (μm)

495 ± 39 (363 to 555) 529 ± 37 (414 to 631) 508 ± 47 (418 to 582) < 0.01

Ectasia

onset*a (months)

41 ± 50 (0.25 to 192) 35 ± 24 (0.20 to 132) 18 ± 13 (1 to 48) 0.06
Postoperative RSB*a (μm) 384 ± 41 (285 to 433) 238 ± 55 (80 to 426) 349 ± 40 (305 to 389) < 0.01‡†
PTA*a (%) 24 ± 6 (15 to 40) 45 ± 10 (23 to 66) 37 ± 4 (32 to 41) < 0.01‡#

PRK photorefractive keratometry, LASIK laser-assisted in situ keratomileusis, SMILE small-incision lenticule extraction, MRSE manifest refractive spherical equivalent, D diopters, CCT central corneal thickness, RSB residual stromal bed, PTA percent tissue altered

*Reported as mean ± SD (range)

Significance between PRK and LASIK

Significance between PRK and SMILE

#Significance between LASIK and SMILE

aTukey HSD