. Author manuscript; available in PMC: 2023 Jan 1.

Published in final edited form as: Alzheimers Dement. 2021 May 13;18(1):65–76. doi: 10.1002/alz.12364

Table 1.

Participant characteristics

Characteristic	Value
N	219
Age at MRI, years (mean ± SD)	66.8 ± 7.5
Age at LP, years (mean ± SD)	64.9 ± 7.5
Age difference between MRI and LP, years (median [IQR])	1.21 [0-4.03]
Sex, % female (n)	58.9% (129/219)
APOE ε4 allele, % positive (n)	34.9% (76/219)
Primary race/ethnicity, n (Caucasian/African American/Asian/Native American/Other)	213 / 3 / 1 / 1 / 1
Education, years (mean ± SD)	16.6 ± 2.3
Montreal Cognitive Assessment (MoCA) (ADRC participants, n = 131)	27.1 ± 2.3
Mini-Mental State Examination (MMSE) (WRAP participants, n = 88)	29.4 ± 0.9
CSF values
Aβ₄₀, ng/mL (mean ± SD)	14.8 ± 4.6
Aβ₄₂, pg/mL (mean ± SD)	908 ± 389
Aβ₄₂/Aβ₄₀ (mean ± SD)	0.06 ± 0.02
pTau₁₈₁, pg/mL (median [IQR])	16.9 [13.3-22.1]
CSF biomarker cutoff groups, n (% of sample)
A−/T−	166 (75.8%)
A−/T+	13 (5.9%)
A+/T−	18 (8.2%)
A+/T+	22 (10.0%)