Table 1:
Distribution of demographic and clinico-pathological variables for enrolled patients across all the 3 study sites.
| Patient Demographic Variables | Site 1 | Site 2 | Site 3 | Total | p-value |
|---|---|---|---|---|---|
| Total number of patients | 39 | 50 | 78 | 167 | |
| Age (in years) | 0.89 | ||||
| Median | 55 | 52 | 51 | 52 | |
| (Range) | (20 – 77) | (19 – 80) | (20 – 88) | (19 – 88) | |
| Gender | 0.38 | ||||
| Male | 8 (20.5%) | 10 (20.0%) | 23 (29.5%) | 41 (24.6%) | |
| Female | 31 (79.5%) | 40 (80.0%) | 55 (70.5%) | 126 (75.2%) | |
| Ethnicity | 0.54 | ||||
| Caucasian | 33 (84.6%) | 46 (92.0%) | 68 (87.2%) | 147 (87.9%) | |
| Non-Caucasian | 6 (15.4%) | 4 (8.0%) | 10 (12.8%) | 20 (12.1%) | |
| Body Mass Index (in kg/m 2 ) | 0.18 | ||||
| Median | 28 | 30.3 | 28.5 | 28.9 | |
| (Range) | (19.0 – 47.0) | (19.9 – 53.8) | (20.5 – 53.4) | (19.0 – 53.8) | |
| Disease Type | 0.23 | ||||
| Benign Conditions | |||||
| Nontoxic Multinodular Goiter | 10 (25.6%) | 13 (26.0%) | 13 (16.6%) | 36 (21.5%) | |
| Nontoxic Solitary Nodule | 0 (0.0%) | 2 (4.0%) | 6 (7.7%) | 8 (4.8%) | |
| Toxic Multinodular Goiter | 0 (0.0%) | 1 (2.0%) | 1 (1.3%) | 2 (1.2%) | |
| Toxic Solitary Nodule | 0 (0.0%) | 1 (2.0%) | 0 (0.0%) | 1 (0.6%) | |
| Graves' Disease | 0 (0.0%) | 4 (8.0%) | 9 (11.5%) | 13 (7.8%) | |
| Thyroiditis (including Hashimoto's) | 0 (0.0%) | 1 (2.0%) | 3 (3.9%) | 4 (2.4%) | |
| Primary Hyperparathyroidism | 21 (53.9%) | 13 (26.0%) | 32 (41.0%) | 66 (39.5%) | |
| Tertiary Hyperparathyroidism | 0 (0.0%) | 0 (0.0%) | 1 (1.3%) | 1 (0.6%) | |
| Concurrent Thyroid and Parathyroid Disease | 1 (2.6%) | 4 (8.0%) | 2 (2.6%) | 7 (4.2%) | |
| Prophylactic Thyroidectomies | 0 (0.0%) | 0 (0.0%) | 1 (1.3%) | 1 (0.6%) | |
| Malignant Conditions | |||||
| Papillary Carcinoma of Thyroid | 7 (17.9%) | 11 (22.0%) | 9 (11.5%) | 27 (16.2%) | |
| Medullary Carcinoma of Thyroid | 0 (0.0%) | 0 (0.0%) | 1 (1.3%) | 1 (0.6%) |