Table 4:
Distribution of tissue misclassification rate for participant surgeons versus PTeye® for excised specimens confirmed with histology. All participant surgeons visually confirmed PGs solely based on their surgical experience and remained blinded to output from PTeye®. Specimens such as diseased entire thyroid lobe/thyroid gland where the tissue identity was obvious to surgeons were not included for analysis.
| Site | Surgeon | Surgeon experience at time of study | Number of specimens confirmed with histology* | Total misclassification versus histology* | Misclassification per histology* specimen | ||
|---|---|---|---|---|---|---|---|
| Surgeon | PTeye® | Surgeon | PTeye® | ||||
| Site 1 | Surgeon A | > 10 years | 28 | 2 | 5 | 0.07 | 0.18 |
| Surgeon B | < 5 years | 12 | 3 | 2 | 0.25 | 0.17 | |
| Site 2 | Surgeon C | > 10 years | 19 | 3 | 1 | 0.16 | 0.05 |
| Surgeon D | < 5 years | 2 | 0 | 1 | 0.00 | 0.50 | |
| Site 3 | Surgeon E | > 10 years | 55 | 5 | 7 | 0.09 | 0.13 |
| Surgeon F | < 5 years | 38 | 10 | 0 | 0.26 | 0.00 | |
| Overall | All surgeons | > 10 years | 103 | 10 | 13 | 0.10 | 0.13 |
| All surgeons | < 5 years | 52 | 13 | 3 | 0.25** | 0.06** | |
| Total | 155 | 23 | 16 | 0.15 | 0.10 | ||
*
Histology = frozen section analysis + permanent histology
**
p-value (Chi-square test) < 0.05.