Table 4.
Summary of 90Y dosimetric phantom and patient studies
| Study | Type of study | Results |
|---|---|---|
| Minarik et al. [111, 112] | Physical phantom | Activity error for liver and 113 mL sphere < 11% |
| Patient study (111In and 90Y Zevalin) |
Comparison to absorbed doses from quantitative 111In SPECT/CT (3 patients) Liver, spleen, kidneys within 30% Lungs within 66% |
|
| Elschot et al. [113] | Patient study (90Y microspheres). Physical phantom | Comparison to absorbed doses from 90Y PET/CT (5 patients): ROIs in liver within approximately 15–20%. ROIs in six-sphere phantom within approximately 5% (mean of all spheres). N.B. Data estimated from diagram |
| Rong et al. [114, 115] | Phantoms, physical and simulated for 90Y Zevalin |
Physical phantom: activity error for 3 hot spheres in warm background < 10%. XCAT MC study: activity error < approximately 12% for spleen, liver, kidneys, heart and lungs |
| Dewaraja et al. [116] | Physical phantom | Activity error for 3 hot spheres (or similar) in warm background < 15%, liver and lung < 4% |