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. 2021 Nov 12;12:6569. doi: 10.1038/s41467-021-26550-y

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a Cluster means from k-Shape clustering of peaks from neuronal and non-neuronal cells in the head of C. intestinalis. Clusters are assigned alphabetical labels according to their half-peak width. Error bands show within-cluster standard deviation. b PCA of peak-features showing how k-Shape clustering maps onto the PCA space. c Inverse transform for each of the input features showing the characteristics of the PCA space. Color intensity and the color bar scales indicate the magnitude of the corresponding feature. d State transition matrix of a Markov chain created from discretized sequences of HNK-1 cell calcium traces and the corresponding (e) state transition graph. f State transition matrix of a Markov chain created from discretized sequences of photoreceptor cell calcium traces and the corresponding (g) state transition graph. Color bar scales in (d) and (f) are transition probability. Numbers on the transition graphs in (e) and (g) also show transition probability. Transition probabilities < 0.1 were excluded to reduce visual clutter.