Table 1.
Baseline characteristics of all episodes of acute leukemia.
| Characteristics | AML episodes (n = 393) | ALL episodes (n = 159) | P |
|---|---|---|---|
| Age, median (IQR) | 56 (49–63) | 45 (31–62) | < 0.001 |
| Male | 205 (52.2) | 73 (45.9) | 0.183 |
| CCI score, median (IQR) | 3 (3–5) | 3 (2–4) | < 0.001 |
| Induction or re-induction chemotherapy (vs. consolidation) | 237 (60.3) | 73 (45.9) | 0.002 |
| Antimold prophylaxis | 220 (56.0) | 11 (6.9) | < 0.001 |
| Posaconazole | 217 (55.2) | 5 (3.1) | |
| Others | 3 (0.8)* | 6 (3.8)† | |
| Duration of neutropenia, median, IQR | 18 (11–28) | 8 (3–15) | < 0.001 |
| IFI episodes | 28 (7.1) | 12 (7.5) | 0.862 |
| Invasive aspergillosis | 21 (5.3)‡ | 7 (4.4) | |
| Invasive candidiasis | 8 (2.0)‡ | 5 (3.1) | |
| Others | 1 (0.3)§ | 0 (0.0) |
Data are shown as number (%), not otherwise specified.
*Other prophylactic agents included 3 micafungin.
†Other prophylactic agents included 3 itraconazole and 3 micafungin.
‡Two episodes had IA and IC simultaneously.
§One cryptococcosis.