Fig. 3. ProteoTracker determines timing for molecular events and shows that ribosome is the most affected protein complex during differentiation of PSCs.
a Differentiation scale determined by the mean distances on T1 and T3 normalized by T3 for selected pathways in iPSC, EB, and hFF. b Differentiation scale determined by distances to iPSC on PCA of the mean Sm and Exp of proteins in each selected pathway in iPSC, hFF, and EB normalized by the distance between hFF and iPSC. c ProteoTracker analysis of ribosomal proteins trajectories in transitions (T1) and (T2). d–g Two-dimensional plots of mean Sm and Exp FCs in H9 ESC, EB, hFF, and RKO against hi12 iPSC. Source data are provided as a Source Data file.