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. 2021 Nov 9;10(13):8. doi: 10.1167/tvst.10.13.8

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Figure 5. — LBI-administered Mertk^−/−Cx3cr1^GFP/+Ccr2^RFP/+ mice showed attenuation of RD at POD 84. LBI-high, LBI-low, and control feed were provided to the mice until POD 84. Severity of RD was assessed using retinal sectioning. Control Mertk^−/−Cx3cr1^GFP/+Ccr2^RFP/+ mice showed severe RD at POD 84 (A and D). Magnified image of the ONL and subretinal space is shown (A-2). Retinal sections of LBI-high (C) and LBI-low (B) Mertk^−/−Cx3cr1^GFP/+Ccr2^RFP/+ mice are shown. Preserved nuclei in ONL were observed in LBI-high (C-2) and LBI-low (B-2) groups compared with those in the control group (A-2). Entire inferior retina (from the OD to ciliary body [CB]) are shown (D, E, and F). ONL nuclei number of each 200 from OD to inferior or superior retina are shown (G). LBI-high (n = 10) and LBI-low (n = 10) groups showed significant attenuation of RD compared with the control group (n = 12). *P < 0.05 compared with the control group.