Table 2.
Baseline characteristics of the participantsa
| Placebo group (n = 40) |
CLE group (n = 39) |
p value | |||
|---|---|---|---|---|---|
| Mean | SD | Mean | SD | ||
| Sex, male/female, n | 16/24 | 15/24 | 0.889 | ||
| Age, years | 56.6 | 4.3 | 56.7 | 5.0 | 0.930 |
| Physical measurements and tests | |||||
| Height, cm | 162.5 | 8.5 | 162.5 | 8.5 | 0.985 |
| Body weight, kg | 69.9 | 8.0 | 70.3 | 7.8 | 0.821 |
| BMI, kg/m2 | 26.4 | 1.8 | 26.6 | 1.5 | 0.664 |
| SBP, mmHg | 122.9 | 12.8 | 119.7 | 14.7 | 0.308 |
| DBP, mmHg | 77.6 | 10.2 | 77.6 | 9.6 | 0.995 |
| Serum inflammatory markers | |||||
| CRP, mg/dL | 0.076 | 0.047 | 0.075 | 0.064 | 0.940 |
| C3, mg/dL | 110.8 | 12.6 | 104.7 | 14.2 | 0.073 |
| C4, mg/dL | 27.5 | 7.0 | 24.0 | 6.0 | 0.037 |
| Fibrinogen, mg/dL | 285.7 | 43.8 | 288.5 | 45.0 | 0.797 |
| Metabolic markers | |||||
| Glucose, mg/dL | 92.3 | 8.7 | 88.5 | 6.4 | 0.031 |
| HbA1c, % | 5.63 | 0.20 | 5.55 | 0.26 | 0.147 |
| Triglyceride, mg/dL | 120.8 | 52.9 | 122.2 | 67.0 | 0.915 |
| Total cholesterol, mg/dL | 231.4 | 36.8 | 221.2 | 37.5 | 0.226 |
| LDL-cholesterol, mg/dL | 148.7 | 31.9 | 138.2 | 31.9 | 0.151 |
| HDL-cholesterol, mg/dL | 58.2 | 11.9 | 58.2 | 16.6 | 0.980 |
BMI body mass index, CLE a mixture of a hot water extract and a supercritical carbon dioxide extract of Curcuma longa, DBP diastolic blood pressure, HbA1c hemoglobin A1c, HDL high-density lipoprotein, CRP C-reactive protein, C3 complement component 3, C4 complement component 4, LDL low-density lipoprotein
aValues represent the means and standard deviations for n = 40 (placebo group) or n = 39 (CLE group). Comparison of sex was performed with the two-tailed Mann Whitney U test. Comparisons of physical measurements and tests, serum inflammatory markers, and metabolic markers were performed with the two-tailed unpaired Student’s t test when variance was homogeneous or the Aspin-Welch t test when variance was heterogeneous