Table 3.
Full-Field ERGs. Amplitude of a- and b-Waves for the SRR, MSR, OP, Flicker 30 Hz and SFCR
| Full-field ERGs | All patients | Control group |
p-values | 95%CI | Group 1a | Control group |
p-values | 95%CI | ||
|---|---|---|---|---|---|---|---|---|---|---|
| SRR | a-wave (μV) | RE | −14.74 ± 18.6 | − 11.39 ± 13.56 | 0.5322 | – | − 10.25 ± 4.23 | −11.39 ± 13.56 | 0.7923 | – |
| LE | −8.0 ± 9.06 | − 6.81 ± 7.36 | 0.6595 | – | − 9.90 ± 4.53 | −6.81 ± 7.36 | 0.2278 | – | ||
| b-wave (μV) | RE | 264.42 ± 76.3 | 210.6 ± 80.49 | 0.0329 | [− 103,0 to − 4,6] | 188.0 ± 55.09 | 210.6 ± 80.49 | 0.4268 | – | |
| LE | 262.03 ± 76.7 | 203.3 ± 77.83 | 0.0194 | [−107,5 to − 9,9] | 182.3 ± 49.46 | 203.3 ± 77.83 | 0.4373 | – | ||
| MSR | a-wave (μV) | RE | −160.21 ± 58.8 | − 196.9 ± 55.01 | 0.0480 | [−73,0 to − 0,33] | −103.7 ± 31.6 | −196.9 ± 55.01 | < 0.0001 | [−131.2 to − 55.2] |
| LE | −159.37 ± 63.6 | − 187.2 ± 48.16 | 0.1369 | – | − 102.1 ± 28.1 | − 187.2 ± 48.16 | < 0.0001 | [− 118.4, to − 51.7] | ||
| b-wave (μV) | RE | 414.67 ± 86.4 | 413.3 ± 102,7 | 0.9626 | – | 331.3 ± 82.24 | 413.3 ± 102,7 | 0.037 | [53.29 to 158.7] | |
| LE | 403.92 ± 92.6 | 421.8 ± 96.90 | 0.5478 | – | 319.3 ± 83.02 | 421.8 ± 96.90 | 0.0085 | [28.61, to 176.4] | ||
| OP | amplitude (μV) | RE | 235.9 ± 106.5 | 570.02 ± 254.9 | < 0.0001 | [198,7 to 469,5] | 309.5 ± 71.32 | 570.02 ± 254.9 | 0.003 | – |
| LE | 252.5 ± 175.8 | 525.93 ± 239.4 | 0.0003 | [135,0 to 411,8] | 292.0 ± 73.8 | 525.93 ± 239.4 | 0.004 | – | ||
|
Flicker 30 Hz |
b-wave (μV) | RE | 90.40 ± 28.5 | 85.46 ± 19.17 | 0.5408 | – | 64.75 ± 9.87 | 85.46 ± 19.17 | 0.0030 | [7.716 to 33.70] |
| LE | 90.13 ± 32.8 | 80.69 ± 17.49 | 0.2798 | – | 61.02 ± 7.56 | 80.69 ± 17.49 | 0.0018 | [8.081 to 31.26] | ||
| SFCR | a-wave (μV) | RE | −13.19 ± 5.72 | − 13.30 ± 13.43 | 0.9699 | – | −9.85 ± 2.38 | −13.30 ± 13.43 | 0.4100 | – |
| LE | −13.62 ± 6.15 | − 14.28 ± 14.72 | 0.8356 | – | − 9.92 ± 3.55 | − 14.28 ± 14.72 | 0.3473 | – | ||
| b-wave (μV) | RE | 65.09 ± 22.6 | 91.08 ± 11.5 | 0.2555 | – | 44.50 ± 14.08 | 91.08 ± 11.5 | < 0.0001 | [36.42 to 56.74] | |
| LE | 64.04 ± 24.7 | 56,89 ± 15.07 | 0.3003 | – | 44.65 ± 14.65 | 56,89 ± 15.07 | 0.0463 | [0.217 to 24.2] | ||
Data are presented as mean ± SD or as numbers. SRR scotopic rod response, MSR maximal scotopic response, OP oscillatory potential, Flicker 30 Hz flicker 30 Hz, SFCR single flash cone response, μV microvolts; RE right eye, LE left eye, CI confidence interval, Amp amplitude
aGroup 1 (n = 11): constituted by a subgroup of patients with evident visual disturbances in their VF. Patients with concentric constriction (17 eyes) and hemi-field defects (5 eyes) patterns