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. Author manuscript; available in PMC: 2021 Nov 13.
Published in final edited form as: Science. 2019 Nov 1;366(6465):599–606. doi: 10.1126/science.aay6485

Fig. 4. Increases in antibody epitope binding signal cluster within households and in postal units.

Fig. 4.

We tested whether individuals with increased EBS indicate new exposures due to pathogen transmission by looking for evidence of spatial clustering among children with increases in EBS. In (A to C), each child (node) is connected by an edge to their postal code (indicated by a central node with an assigned value, 2 through 7). Children shown as single nodes were the only children studied from their postal code. Children from the same household are connected by an edge and encircled by dashed gray ovals. Each of the three viruses where increases in EBS were most common are shown: (A) adenovirus C, (B) influenza A virus, and (C) respiratory syncytial virus. Children with significantly increased EBS for the pathogen (indicating exposure during the interval) are highlighted with red circles and those with decreased or unchanged EBS with gray circles.