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. 2021 Nov 13;12(11):1082. doi: 10.1038/s41419-021-04358-4

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A Workflow illustrating collection and processing of single-cell transcriptome of OCs, control ovary, and embryo. B, C OCs and embryo cell clusters from 10× Genomics scRNA-seq analysis visualised by UMAP. D The proportion of diverse cell types across different samples. E Heatmap displaying the expression patterns of specific markers in each cell type. F Violin plots exhibiting the expression of representative markers across diverse cell types. G Scatter plots showing the gene expression patterns of type C0 (x axis) and C1 (y axis). H GSEA analysis of C0 displaying its’ malignant characteristics. I Relationship of C0 and other cell types.