BAG3 is used as the key word to screen for research papers since 2011 in the Web of Science data base. The reviews or comments are filtered out, and the remaining citations were exported to Citespace for cluster analysis based on reference. Five major clusters including cancer, cardiomyopathy, actin dynamics, protein aggregation and viral production and three minor cluster such as cancer cell resistance, cancer cell death, BAG3 mutations are labeled in the diagram.